How does systemic FL2 enter the body?

Systemic fluoride enters the body primarily through ingestion, which includes fluoride that is consumed via food, beverages, and dietary supplements. This method is significant because fluoride becomes incorporated into the body's systems at a systemic level, aiding in the development of strong teeth by promoting mineralization and helping to prevent dental caries.

When fluoride is ingested, it travels through the bloodstream and can have beneficial effects on the developing teeth in children as well as provide a level of protection against tooth decay in individuals of any age. This is different from topical fluoride, which is applied directly to the teeth and works primarily on the surface to strengthen enamel and reverse early stages of decay.

Other methods of potential fluoride entry, such as inhalation or skin absorption, are not typical pathways for fluoride to exert its systemic benefits. Inhalation of fluoride is mostly associated with occupational exposure in certain industrial settings, while absorption through the skin does not provide a significant route for fluoride to enter the bloodstream in a manner that supports dental health. Thus, the most accurate and relevant method of systemic fluoride entry is through ingestion.